Trust me, when I tell you: You could stay in Cape Town for a month and not see it all! The city has a lot of layers, and, like an onion, you unpeel one after another, the longer you stay. But since most of us don't have that much time, I've created this itinerary, that includes Cape Town, the winelands, parts of the coast and a good mix of food, wine, sightseeing and outdoor activities. A few infos about this itinerary:
Since many of the Cape Town foods & crafts markets only happen on the weekend, I would recommend you mix and match the days and visit one of the markets when they are open
I added multiple restaurant recommendations, just swap them for whatever place you like most
If you don't want to take the sightseeing bus, you could do all of those trips with your rental car of course but for the ease of just settling in during the first few days, I really recommend you skip driving and just let someone drive you!