This street is the extension of the famous Long Street Party Mile. Here, you'll find countless great delis, cafés, bars, and restaurants (just like in neighbouring Bree Street). In addition to that, Kloof Street offers amazing Table Mountain views.
It's quite safe to walk, during the day you'll be fine. At night, only walk along Kloof Street and not the side streets and only in a bigger group. If you are only one, two or 3 people, I'd recommend you take an Uber or Bolt.